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Menopausal Hormone Therapy (MHT) discontinuation and shortages Feb 2024

Australia

Please note that Femoston-Conti 1/5 has been delisted from the PBS and is only available on private script from 1 December 2023. Patients who have been prescribed Femoston-Conti 1/5 before 1 December 2023 will be able to have it dispensed at the PBS listed price until 1 March 2024. We understand that the delisting is a commercial decision made by the sponsor. While private script prices fluctuate between pharmacies, Femoston-Conti 1/5 is currently being sold at a large pharmacy chain for $11.99 on a private script.

Product
Composition
Date of deletion
Climara 25
25mcg oestradiol transdermal patch
Deleted
Climara 50
50mcg oestradiol transdermal patch
15 Mar 2024
Climara 75
75mcg oestradiol transdermal patch
Deleted
Climara 100
100mcg oestradiol transdermal patch
Deleted

There are a number of MHTs that are currently unavailable. Please note that the TGA has approved some unregistered products for supply under Section 19A.

Product
Composition
Expected supply due
Section 19A Approved Equivalent
Estradot 25
25mcg oestradiol
26 Apr 2024
Estramon oestradiol 50mcg
Estradot 37.5
37.5mcg oestradiol
17 May 2024
Estramon oestradiol 37.5mcg
Estradot 50
50mcg oestradiol
26 Apr 2024
Estramon oestradiol 50mcg
Estradot 75
75mcg oestradiol
17 May 2024
Estramon oestradiol 75mcg
Estradot 100
100mcg oestradiol
17 May 2024
Estramon oestradiol 100mcg
Estraderm MX 25
25mcg oestradiol
Available
 
Estraderm MX 75
75mcg oestradiol
15 Mar 2024
 
Estraderm MX 100
100mcg oestradiol
Available
 
Estalis Sequi 50/140
50mcg 17β oestradiol/140mcg norethisterone acetate
Unavailable
 
Estalis Sequi 50/250
50mcg 17β oestradiol/250mcg norethisterone acetate
1 Mar 2024
 
Estalis Conti 50/140
50mcg 17β oestradiol/140mcg norethisterone acetate
Available
 
Estalis Conti 50/250
50mcg 17β oestradiol/250mcg norethisterone acetate
Available
 

The AMS Guide to MHT Doses (Australia only) provides a guideline to approximately equivalent doses of the different MHT/HRT products in Australia.

New Zealand

A list of patch availability is provided below.

Dose
Estradot
Viatris
Mylan
25mcg
Low supply
n/a
Unavailable
50mcg
Low supply
Unavailable
Unavailable
75mcg
Unavailable
Unavailable
Unavailable
100mcg
Unavailable
Available
Unavailable

More information can be found at here

The AMS Guide to MHT Doses (New Zealand only) provides a guideline to approximately equivalent doses of the different MHT/HRT products in New Zealand. 

Content created 8 February 2024

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