Facebook Follow AMS on Linkedin Follow us on Twitter @amsCoolAgain AMS on Instagram

Early Menopause

The following topics concerning early menopause may be found in the AMS Information Sheets. 

Spontaneous Premature Ovarian Insufficiency

Menopause in women younger than 40 years of age is called premature menopause. If this happens spontaneously it is called premature ovarian failure. Premature ovarian failure affects about 1 in a 100 women. Around 8 per 100 women have premature menopause due to other causes such as chemotherapy or surgery. Menopause occurring between 40-45 years of age is called early menopause, affecting approximately 5% of women. Menopause can occur spontaneously or can be a result of chemotherapy (See AMS information sheet:- Early Menopause Due to Chemotherapy) or ovarian surgery. There is no evidence that early menopause is brought on by the use of oral contraceptives, fertility drugs or artificial hormones in the environment. However, smoking or a family history of early menopause is associated with an earlier onset of menopause. Diagnosis of early ovarian failure often has long term physical and psychological consequences, so women may need emotional support and ongoing medical follow-up.


pdfAMS Spontaneous Premature Ovarian Insufficiency470.86 KB

Early Menopause due to Chemotherapy and Radiotherapy

Chemotherapy is usually administered as part of cancer treatment but may also be given to women with severe connective tissue disorders such as systemic lupus erythematosis or kidney disease such as Wegener’s granulomatosis. Survival rates for many cancers in women of reproductive age are increasing. However, many treatments used to combat the disease carry a substantial risk for future infertility. Chemotherapy is toxic to the ovaries causing loss of eggs and destruction of the supporting ovarian tissue. This may cause temporary cessation of menstrual periods or early menopause which can develop quickly or gradually.


pdfAMS Early Menopause due to Chemotherapy and Radiotherapy537.99 KB

Surgical Menopause

Menopause means the final menstrual period. The average age of menopause is around 51 years, but most women will start to notice menopausal symptoms from around 47 years.  This may be noticed as the onset of hot flushes, night sweats or vaginal dryness or a change in menstrual periods to more infrequent and sometimes heavier menstrual bleeding (1). Removal of both ovaries (bilateral oophorectomy) before the normal menopause is called “surgical menopause”.


pdfAMS Surgical Menopause464.47 KB


AMS New directions in women's health 

Note: Medical and scientific information provided and endorsed by the Australasian Menopause Society might not be relevant to a particular person's circumstances and should always be discussed with that person's own healthcare provider.

These Information Sheets may contain copyright or otherwise protected material. Reproduction of this Information Sheet by Australasian Menopause Society Members and other health professionals for clinical practice is permissible. Any other use of this information (hardcopy and electronic versions) must be agreed to and approved by the Australasian Menopause Society.


Content updated September 2018

Print Email


Facebook Follow AMS on Linkedin Follow us on Twitter @amsCoolAgainAMS on Instagram