ESHRE Guideline on premature ovarian insufficiency

ESHRE Guideline on premature ovarian insufficiency website This updated guideline offers best practice recommendations for the care of women with with both primary and secondary premature ovarian insufficiency (POI). POI is a clinical condition defined by the loss of ovarian function indicated by irregular menstrual cycles together with biochemical confirmation of ovarian insufficiency before the age of 40.

Women with POI have unique needs. They may not only suffer from symptoms associated with estrogen deficiency, but can also experience other issues, with a significant impact on their quality of life and later health outcomes. POI can have significant effects on fertility, bone health, cardiovascular health, sexual function, psychological health and neurological function.

The impact of POI on these different domains and the treatment options for each along with monitoring needs where relevant are all discussed in the guideline.

In addition to hormone therapy the guideline also covers non-hormonal and complementary treatments, lifestyle interventions and puberty induction.

This guideline is an updated version and replaces the ESHRE Guideline on the management of women with POI (2016) (see https://doi.org/10.1093/humrep/dew027)

Guideline

Guideline on premature ovarian insufficiency

ESHRE Guideline on premature ovarian insufficiency - full version15.76 MB

Acknowledgements (from the Guideline)

We gratefully acknowledge the contribution of our engaged, funding, partner and collaborating organisations:

ESHRE
Our partner organisations which co-funded the guideline: American Society for Reproductive Medicine (ASRM), International Menopause Society (IMS), and The Australian National Health and Medical Research Council (NHMRC) through the funded Centre for Research Excellence in Women’s Health in Reproductive Life (CRE WHiRL)
Our collaborating and engaged consumer groups.
- American College of Obstetricians and Gynecologists (ACOG)
- Australasian Menopause Society (AMS)
- British Menopause Society (BMS)
- European Menopause and Andropause Society (EMAS)
- Endocrine Society (ES)
- International Society of Gynecological Endocrinology (ISGE)
- North American Menopause Society (NAMS)
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG)
- Royal College of Obstetricians and Gynaecologists (RCOG)