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Using progesterone for hot flushes shown safe for women's cardiovascular health

Treatment with progesterone, a naturally occurring hormone that has been shown to alleviate severe hot flushes and night sweats in post-menopausal women, poses little or no cardiovascular risk, according to a new study by the University of British Columbia and Vancouver Coastal Health.

The findings, published in PLOS ONE, help to dispel a major impediment to widespread use of progesterone as a treatment for hot flashes and night sweats, said lead author Dr. Jerilynn C. Prior, a professor of endocrinology and the head of Centre for Menstrual Cycle and Ovulation Research.

For decades, women used a combination of synthetic estrogen and progesterone to reduce the frequency and severity of hot flashes and night sweats, as well as to prevent osteoporosis. Use of this so-called "hormone replacement therapy" dropped dramatically after 2002, when a large study revealed that it increased risk of heart disease, breast cancer, strokes and other serious conditions.

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Web predicts disease outbreak

The habit of Googling for an online diagnosis before visiting a GP can provide early warning of an infectious disease epidemic.

In a new study published in Lancet Infectious Diseases, internet-based surveillance has been found to detect infectious diseases such Dengue Fever and Influenza up to two weeks earlier than traditional surveillance methods.

Senior author of the paper titled Internet-based surveillance systems for monitoring emerging infectious diseases , QUT Senior Research Fellow Dr Wenbiao Hu said when investigating the occurrence of epidemics, spikes in searches for information about infectious diseases could accurately predict outbreaks of that disease.

Dr Hu, based at QUT's Institute for Health and Biomedical Innovation, said there was often a lag time of two weeks before traditional surveillance methods could detect an emerging infectious disease.

"This is because traditional surveillance relies on the patient recognising the symptoms and seeking treatment before diagnosis, along with the time taken for health professionals to alert authorities through their health networks," Dr Hu said.

"In contrast, digital surveillance can provide real-time detection of epidemics."

Dr Hu said the study found by using digital surveillance through search engine algorithms such as Google Trends and Google Insights, detecting the 2005-06 avian influenza outbreak "Bird Flu" would have been possible between one and two weeks earlier than official surveillance reports.

"In another example, a digital data collection network was found to be able to detect the SARS outbreak more than two months before the first publications by the World Health Organisation (WHO)," he said.

"Early detection means early warning and that can help reduce or contain an epidemic, as well alert public health authorities to ensure risk management strategies such as the provision of adequate medication are implemented."

Dr Hu said the study found social media and microblogs including Twitter and Facebook could also be effective in detecting disease outbreaks.

Read more …Web predicts disease outbreak